Endocrine Abstracts

Context: Recombinant human GH (rhGH) is indicated for the treatment of adult subjects with GH deficiency (GHD). However, conflicting data are available on the efficacy of rhGH treatment in elderly GHD patients.Objective: To assess the efficacy of rhGH treatment in elderly GHD subjects.Methods: We searched PubMed, Cochrane Library, Web of Science, and EMBASE.Study selection: Eligible studies included GHD patie...

Background: The long-term prevalence of adrenal insufficiency after transsphenoidal surgery for GH secreting pituitary adenomas was unknown. However, recently a single study reported a high prevalence of adrenal insufficiency after surgical and/or medical treatment without postoperative radiotherapy in acromegalic patients.Aim: To assess the prevalence and incidence rate of adrenal insufficiency in consecutive patients during long-term follow-up after su...